01 - Bring a large pot of salted water to boil. Cook fettuccine according to package directions until al dente. Drain, reserving 1/2 cup pasta water, and set aside.
02 - Combine chili powder, cumin, smoked paprika, garlic powder, salt, and pepper in a small bowl. Rub spice mixture evenly over both sides of chicken breasts.
03 - Heat olive oil in a large skillet over medium-high heat. Add chicken and cook 5-7 minutes per side until cooked through with an internal temperature of 165°F and lightly charred. Transfer to a cutting board, let rest 5 minutes, then slice into thin strips.
04 - In the same skillet, add more oil if needed. Sauté red onion, bell peppers, and jalapeño for 4-5 minutes until softened and slightly caramelized. Remove from pan and set aside.
05 - Reduce heat to medium. Melt butter in the skillet, then add minced garlic. Sauté 30 seconds until fragrant, taking care not to burn.
06 - Pour in heavy cream and milk. Bring to a gentle simmer, whisking occasionally. Stir in Parmesan cheese, salt, pepper, and chipotle powder. Cook 3-4 minutes until sauce is smooth and slightly thickened.
07 - Add cooked pasta and reserved vegetables to the sauce. Toss to coat thoroughly. If sauce is too thick, add a splash of reserved pasta water to reach desired consistency.
08 - Squeeze fresh lime juice over the pasta mixture. Top with sliced chicken breasts.
09 - Sprinkle chopped cilantro over the dish. Serve immediately with extra lime wedges on the side.